CAS: 1799725-26-0

GSK180 is a selective competitive inhibitor of kynurenine 3-monooxygenase (KMO; IC50: ~6 nM), an enzyme involved in tryptophan metabolism.

GSK-180 is a research chemical that has shown potential in various fields of study. It has a unique mechanism of action, primarily targeting 5-HT2 receptors and 5-HT1 receptors. This compound has been used in hybridization studies to investigate the interactions between neurotransmitters and their receptors. Additionally, GSK-180 has been explored for its effects on gamma-aminobutyric acid (GABA) receptors. Apart from its role in neuroscience research, GSK-180 is also utilized in the synthesis of various compounds. It serves as an intermediate for the production of medoxomil, carbostyril, gadolinium complexes, dopamine derivatives, noscapine synthesis intermediates, and aptamer ligation. Due to its reactive nature and diverse applications, GSK-180 offers scientists and researchers a valuable tool for exploring different aspects of chemistry and biology. Its versatility makes it an essential component in laboratories worldwide.