CAS: 1818294-32-4

Spdp-PEG6-NHS ester is a heterobifunctional PEG (polyethylene glycol) compound that is commonly used in pegylation processes. It contains a succinimidyl group (NHS) at one end and a PEG linker with six ethylene glycol units at the other end. This unique structure allows for efficient conjugation of biomolecules to PEG, enhancing their stability, solubility, and bioavailability. The N-hydroxysuccinimide (NHS) group reacts with primary amines on proteins or peptides, forming stable amide bonds. This reaction, known as NHS ester chemistry, is widely utilized in the development of PEGylated products for various applications in pharmaceuticals and biotechnology. Spdp-PEG6-NHS ester provides researchers with a versatile tool for modifying biomolecules and creating novel PEG products with improved properties.

SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.