2,3,4,5,6-Pentachlorobiphenyl, with the CAS number 18259-05-7, is a chlorinated biphenyl compound that belongs to the class of polychlorinated biphenyls (PCBs). This substance is characterized by the presence of five chlorine atoms attached to a biphenyl structure, which consists of two phenyl rings connected by a single bond. The chlorination pattern significantly influences its chemical properties, including its hydrophobicity, thermal stability, and resistance to degradation. 2,3,4,5,6-Pentachlorobiphenyl is typically a solid at room temperature and exhibits low volatility. It is known for its environmental persistence and bioaccumulation potential, raising concerns regarding its toxicity and ecological impact. PCBs, including this compound, have been associated with various adverse health effects in humans and wildlife, leading to regulatory restrictions on their use and disposal. Analytical methods such as gas chromatography-mass spectrometry (GC-MS) are commonly employed to detect and quantify this compound in environmental samples.

2,3,4,5,6-Pentachlorobiphenyl

18259-05-7: 1,1'-Biphenyl, 2,3,4,5,6-pentachloro-, 2,3,4,5,6-Pentachloro-1,1’-Biphenyl, Biphenyl, 2,3,4,5,6-pentachloro-, Cb 116, Pcb 116, Pcb No 116, 2,3,4,5,6-Pentachlorobiphenyl

PCB No. 116

2,3,4,5,6-Pentachlorobiphenyl is a complex compound that belongs to the group of polychlorinated biphenyls. It has been shown to induce autoimmune diseases in mice and rats by activating the immune system. The enzyme activity increases when 2,3,4,5,6-pentachlorobiphenyl binds to the ryanodine receptor (RYR) and induces an increase in intracellular calcium levels. This leads to increased production of cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). In vitro assays have demonstrated that 2,3,4,5,6-pentachlorobiphenyl also has effects on bacterial strains.

CAS 18259-05-7: 2,3,4,5,6-Pentachlorobiphenyl

PCB No. 116

Ref: 04-C20011600

PCB No. 116

Ref: TR-DRE-C20011600

2,3,4,5,6-Pentachlorobiphenyl

Ref: 3D-TAA25905

1,1'-Biphenyl, 2,3,4,5,6-pentachloro-

Ref: IN-DA0023ZQ