Thiazole, 5-phenyl- is an organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing both sulfur and nitrogen atoms. The presence of a phenyl group at the 5-position of the thiazole ring enhances its chemical properties, making it a valuable compound in various chemical applications. This compound typically exhibits a range of biological activities, which can include antimicrobial and antifungal properties, making it of interest in pharmaceutical research. Thiazole derivatives are often utilized in the synthesis of agrochemicals and dyes due to their ability to participate in various chemical reactions, such as nucleophilic substitutions and cycloadditions. The compound is generally stable under standard conditions but may undergo reactions typical of thiazole derivatives, such as electrophilic aromatic substitution. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken. Overall, thiazole, 5-phenyl- is a significant compound in organic chemistry with diverse applications.

Thiazole,5-phenyl-

5-Phenylthiazole

5-Phenylthiazole is a drug substance that is used in the manufacture of bronchodilators. It is also an intermediate in the synthesis of other drugs, such as antihistamines and antipsychotics. 5-Phenylthiazole is biosynthesized by the condensation of two molecules: hydroxy group and carboxy group. This reaction requires enzymes and coenzymes to proceed. The enzyme phosphatidylinositol 3-kinase catalyzes the reaction, which is mediated by alkylaminocarbonyl transferase. 5-Phenylthiazole can be found as a salt form or as a free base, depending on its use.
5-Phenylthiazole has been shown to have bronchodilatory effects in animals, which are due to its ability to inhibit potassium channels in lung cells.

CAS 1826-13-7: Thiazole,5-phenyl-

5-Phenylthiazole

Ref: 54-OR91034

5-Phenylthiazole

Ref: 10-F209295

5-Phenylthiazole

Ref: 3D-FP28978

Thiazole, 5-phenyl-

Ref: IN-DA002403