2-(Trimethylsilyl)acetonitrile, with the CAS number 18293-53-3, is an organosilicon compound characterized by the presence of a trimethylsilyl group attached to an acetonitrile moiety. This compound typically appears as a colorless to pale yellow liquid and is known for its relatively low volatility and high stability under standard conditions. It features a nitrile functional group, which imparts polar characteristics, making it useful as a solvent and reagent in various organic synthesis applications. The trimethylsilyl group enhances the compound's solubility in organic solvents and can also serve as a protecting group for functional groups in synthetic chemistry. Additionally, 2-(Trimethylsilyl)acetonitrile is often employed in the preparation of other chemical compounds and can participate in nucleophilic reactions due to the presence of the nitrile carbon. Its unique structure and properties make it valuable in both academic research and industrial applications, particularly in the fields of organic synthesis and materials science.

2-(Trimethylsilyl)acetonitrile

18293-53-3: (Cyanomethyl)trimethylsilane, (Trimethylsilyl)acetonitrile, 2-(Trimethylsilyl)acetonitrile, Acetonitrile, (trimethylsilyl)-, Acetonitrile, 2-(trimethylsilyl)-

Acetonitrile, 2-(trimethylsilyl)-

Trimethylsilylacetonitrile

(Trimethylsilyl)acetonitrile, 95%

Trimethylsilylacetonitrile is a functional group that is used as a reactant in organic reactions. It is a nucleophilic reagent that reacts with an electrophilic compound to form a new carbon-carbon bond. Trimethylsilylacetonitrile can be deprotonated by the base hydrochloric acid, which leads to nucleophilic attack of the carbonyl group or radical coupling. Reaction rate increases with the presence of an acid catalyst and methoxy groups on the carbonyl group.

CAS 18293-53-3: 2-(Trimethylsilyl)acetonitrile

Acetonitrile, 2-(trimethylsilyl)-

Ref: IN-DA00249I

Trimethylsilylacetonitrile

Ref: 10-S25285

(Trimethylsilyl)acetonitrile, 95%

Ref: BD-BD49372

2-(Trimethylsilyl)acetonitrile

Ref: 54-OR96769

Trimethylsilylacetonitrile

Ref: 3D-FT76209