CAS 183208-34-6: 5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One

5-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one is a cancer drug that is a potent inhibitor of angiogenesis. This compound has been shown to inhibit tumor growth in vitro and in vivo. 5-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one also shows antiangiogenic activity in mouse models of cancer. The antitumor effects of this drug are mediated by inhibition of the protein tyrosine kinases VEGF receptor 1 (VEGFR1) and VEGFR2. Sunitinib is an oral anticancer agent used for the treatment of metastatic renal cell carcinoma and other solid tumors. It has been found to be active against a variety of human cancers including melanomas, lung cancers, breast

5-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one