CAS: 18326-06-2

2-Acetoxy-3-deacetoxycaesaldekarin E shows significant dose-dependent inhibitory effects on Plasmodium falciparum FCR-3/A2 growth in vitro.

[(4aR,11bS)-1-Acetyloxy-4a-hydroxy-4,4,7,11b-tetramethyl-2,3,5,6-tetrahydro-1H-naphtho[2,1-F][1]benzofuran-2-yl] acetate is a bioactive diterpene, primarily sourced from the seeds of the Neem tree (Azadirachta indica). Known as a key component in natural pesticide formulations, this compound exhibits a complex mode of action, primarily functioning by disrupting hormonal systems and interfering with the normal development and metamorphosis of insect pests. It effectively inhibits feeding and reproduction in a wide range of agricultural pests. Researchers have been particularly interested in its application due to its potential as a biopesticide that offers an environmentally friendly alternative to synthetic pesticides. By impairing larval development and preventing moulting, this compound exhibits promising efficacy in crop protection. Moreover, due to its biodegradability and minimal toxicity towards non-target organisms, this compound is highly valued in integrated pest management strategies. Its multifaceted action and natural origin make it a subject of ongoing research in the field of agricultural science.