Alpha-methylbenzyl isocyanate, with the CAS number 1837-73-6, is an organic compound characterized by its isocyanate functional group (-N=C=O) attached to an alpha-methylbenzyl moiety. This compound typically appears as a colorless to pale yellow liquid and has a distinctive, pungent odor. It is known for its reactivity, particularly in forming urethane and urea derivatives through reactions with alcohols and amines. Alpha-methylbenzyl isocyanate is used in the synthesis of various chemicals, including pharmaceuticals and agrochemicals. Due to the presence of the isocyanate group, it can be hazardous, exhibiting potential toxicity and irritant properties, particularly to the skin, eyes, and respiratory system. Proper handling and safety precautions are essential when working with this compound, including the use of personal protective equipment and working in a well-ventilated area. Its reactivity and functional versatility make it a valuable intermediate in organic synthesis, although its hazardous nature necessitates careful management in laboratory and industrial settings.

alpha-methylbenzyl isocyanate

1837-73-6: Benzene, (1-isocyanatoethyl)-,  (s)-(-)-(1-Isocyanatoethyl)benzene, alpha-Methylbenzyl isocyanate

(1-Isocyanatoethyl)benzene

Alpha-methylbenzyl isocyanate is an organic compound that belongs to the class of chiral compounds. It has a variety of chemical structures, including cyanate and fluorimetric. This compound was first synthesized in 1887 by the reaction of piperazine with ethylene and carbodiimides, which yielded a racemic mixture of alpha-methylbenzyl isocyanate. Alpha-methylbenzyl isocyanate has antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. It also has antibiotic activity against Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii. Alpha-methylbenzyl isocyanate can be used in analytical methods for determining the concentration of inorganic acid or alkali metal ions in a solution by measuring the change in optical rotation or fluorescence intensity.

CAS 1837-73-6: alpha-methylbenzyl isocyanate

(1-Isocyanatoethyl)benzene

Ref: 54-OR941358

α-methylbenzyl isocyanate

Ref: 3D-FM45748

(1-Isocyanato-ethyl)-benzene

Ref: 10-F025633