Benzofuran, 2-phenyl- is an organic compound characterized by its fused benzene and furan rings, with a phenyl group attached at the 2-position of the benzofuran structure. This compound typically exhibits a white to pale yellow crystalline appearance and is known for its aromatic properties, which contribute to its stability and reactivity. It is relatively non-polar, making it soluble in organic solvents but less so in water. Benzofuran derivatives are often studied for their potential biological activities, including anti-inflammatory and anticancer properties. The compound's structure allows for various substitution patterns, which can influence its chemical behavior and interactions. Additionally, it may undergo typical electrophilic aromatic substitution reactions due to the presence of the aromatic rings. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if inhaled or ingested. Overall, benzofuran, 2-phenyl- serves as an important building block in organic synthesis and medicinal chemistry.

Benzofuran, 2-phenyl-

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2-Phenylbenzofuran

2-Phenylbenzofuran is a receptor binding compound that binds to the aryl halide binding site of the hepg2 cell. It inhibits the uptake of monoamine neurotransmitters, such as serotonin and dopamine, by competitive inhibition. 2-Phenylbenzofuran has shown an inhibitory effect on glycyrrhiza uralensis, which is a plant used in traditional Chinese medicine for the treatment of infectious diseases. 2-Phenylbenzofuran also blocks proton channels and inhibits the inflammatory response induced by bacterial lipopolysaccharides (LPS) in human macrophages. This compound has been shown to decrease insulin resistance in mice with diet-induced obesity by inhibiting diacylglycerol acyltransferase 1 (DGAT1).

CAS 1839-72-1: Benzofuran, 2-phenyl-

2-Phenylbenzofuran

Ref: IN-DA003HV9

2-Phenylbenzofuran

Ref: 54-OR340156

2-Phenylbenzofuran

Ref: 3D-BAA83972