CAS 18531-94-7: (+)-BINOL

It is used in biosynthetic preparation for enantioselective oxidation of naphthols to binaphthyldiols with horseradish peroxidase catalyst. A chiral auxiliary used in the catalytic asymmetric oxidation of sulfides to sulfoxides. Chiral lanthanide triflates formed from binaphthol serve as catalysts for asymmetric Diels-Alder reactions. Derivatives of binaphthol have recently found use in asymmetric Claisen rearrangements and asymmetric epoxidations.5 The lithium aluminum hydride derivative of these diols (BINAP-H) has been used extensively for the reduction of ketones. Chiral binapthol imminium salt precursor. Salts were used for an asymmetric epoxidation of olefins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

(R)-1,1'-Bi-2-Naphthol is an organic compound that is made from the hydrogenation of 2-naphthol. The sodium salts of this compound are chiral and can be used to synthesize racemic mixtures with a high degree of optical purity. The x-ray crystal structures of (R)-1,1'-Bi-2-Naphthol have been studied in detail and show that this molecule exhibits intermolecular hydrogen bonding interactions. It also has a steric interaction with the amine group which prevents rotation about the C3-C4 bond. Other interesting features include intramolecular hydrogen bonding interactions between the hydroxyl group and the alkanoic acid. This molecule also has a hydrophobic region consisting of three methyl groups that are connected to fatty acids.

(R)-2,2'-Dihydroxy-[1,1']-binaphthyl

Applications R-(+)-1,1'-Bi-2-Naphthol is used in biosynthetic preparation for enantioselective oxidation of naphthols to binaphthyldiols with horseradish peroxidase catalyst. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Sridhar, M., et al.: Tetrahedron Lett., 38, 5695 (1997)

R-(+)-1,1'-Bi-2-naphthol, 99% (R)-BINOL