CAS: 1857417-10-7

MI-538 is a novel cytostatic drug that exhibits selective toxicity to leukemia cells. The compound has been shown to inhibit proliferation of leukemia cells in vivo and in vitro. MI-538 is a molecule inhibitor that interacts with the cyanoindole target, which is involved in cellular differentiation, cell cycle progression, and chromosomal stability. In vivo studies have shown that MI-538 has a good pharmacokinetic profile and does not accumulate in the body. It has also been shown to have an optimized pharmacokinetic profile and does not cause any adverse effects on healthy cells.

MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).

MI-538