Trodusquemine, also known by its chemical name, is a synthetic compound that has garnered interest in the field of biochemistry and pharmacology. It is primarily recognized for its role as a selective inhibitor of protein phosphatase 2A (PP2A), an enzyme that plays a crucial role in various cellular processes, including cell growth and division. The inhibition of PP2A by trodusquemine has potential implications in cancer research, as it may influence tumor growth and proliferation. The compound exhibits a complex molecular structure, which contributes to its biological activity. Trodusquemine has been studied for its effects on metabolic pathways and its potential therapeutic applications, particularly in the context of obesity and metabolic disorders. Additionally, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile. Overall, trodusquemine represents a significant area of research in drug development, particularly for conditions related to cellular signaling and metabolic regulation.

Trodusquemine

186139-09-3: Cholestane-7,24-diol, 3-[[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]amino]-, 24-(hydrogen sulfate), (3β,5α,7α,24R)-, Aminosterol 1436, MSI 1436, Trodusquemine

Inhibitor of protein tyrosine phosphatase PTP1B

MSI-1436

MSI-1436 is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)

CAS 186139-09-3: Trodusquemine

Trodusquemine

Ref: 3D-BT168546

Trodusquemine

Ref: TR-T891970

MSI-1436

Ref: IN-DA00ABOH

MSI-1436

Ref: TM-T12116