CAS 1867-73-8: N6-Methyladenosine
Formula:C11H15N5O4
InChI:InChI=1S/C11H15N5O4/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11,17-19H,2H2,1H3,(H,12,13,14)/t5-,7-,8-,11-/m1/s1
InChI key:InChIKey=VQAYFKKCNSOZKM-IOSLPCCCSA-N
SMILES:O[C@H]1[C@H](N2C=3C(N=C2)=C(NC)N=CN3)O[C@H](CO)[C@H]1O
Synonyms:- (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methylaminopurin-9-yl)oxolane-3,4-diol
- 2-(Hydroxymethyl)-5-(6-methylaminopurin-9-yl)oxolane-3,4-diol
- 6-Methyladenosine
- 6-Methylamino-9-β-<span class="text-smallcaps">D</span>-ribofuranosylpurine
- 6-Methylaminopurine <span class="text-smallcaps">D</span>-riboside
- 6-Methylaminopurine ribonucleoside
- 6-Methylaminopurine riboside
- 9-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-N<sup>6</sup>-methylaminopurine
- Adenosine, N-methyl-
- N-Methyladenosine
- N-methyl-9-alpha-L-ribofuranosyl-9H-purin-6-amine
- See more synonyms
Sort by
Found 10 products.
N6-Methyladenosine
CAS:N6-methyladenosine (m6A) is a modified form of adenosine that contains a methyl group at the N6 position and has a high importance in epigenetics. Among other nucleoside modifications found in mRNA, N6-methyladenosine is the most common and abundant in eukaryotes, and is related to some cancers and viral infections (Huafei, 2020). Moreover, N6-methyladenoside has been reported to regulate RNA abundance in the SARS-CoV-2 infection (Zhang, 2021)Formula:C11H15N5O4Purity:Min. 98.0 Area-%Color and Shape:White PowderMolecular weight:281.27 g/molN6-Methyladenosine
CAS:Controlled ProductApplications N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine. References Miura, G. et al.: Nat. Chem. Biol., 11, 903 (2015); Deng, X. et al.: Nucl. Acids Res., 43, 6557 (2015); Chem. and Eng. News, p.35, Feb. 18, 2019Formula:C11H15N5O4Color and Shape:Off-WhiteMolecular weight:281.27(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(Methylamino)-9H-Purin-9-Yl)Tetrahydrofuran-3,4-Diol
CAS:(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(Methylamino)-9H-Purin-9-Yl)Tetrahydrofuran-3,4-DiolPurity:97%Molecular weight:281.27g/mol(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:281.2720031738281N6-Methyladenosine-13C
CAS:Controlled ProductFormula:C1013CH15N5O4Color and Shape:Off-WhiteMolecular weight:286.26N6-methyladenosine
CAS:N6-methyladenosine (NSC-29409), a methylated adenine residue, is an endogenous urinary nucleoside product of the degradation of transfer ribonucleic acid (tRNA)Formula:C11H15N5O4Purity:97.43% - 99.66%Color and Shape:SolidMolecular weight:281.27
