CAS: 1884710-81-9

Cbz-B3A is a potent inhibitor of mTORC1 signalling, inhibits phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks translation by 68%.

Cbz-B3A

Cbz-B3A is a cytosolic protein that exemplifies the inhibition of the rapamycin complex. It has been shown to inhibit cancer and human diseases, such as leukemia. Cbz-B3A interacts with mammalian cellular molecules, coordinating cellular growth and translation. It also inhibits the cytosolic protein synthesis of ribosomes. This interaction leads to a decrease in the production of proteins, which may lead to cell death.