![(3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F336939-3r-4s-1-4-fluorophenyl-3-3-4-fluorophenyl-3-oxopropyl-4-4-hydroxyphenyl-azetidin-2-one.webp&w=3840&q=75)
CAS 191330-56-0: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Formula:C24H19F2NO3
InChI:InChI=1S/C24H19F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21,23,28H,13-14H2/t21-,23-/m1/s1
InChI key:InChIKey=UEPZDXMEEKCJSP-FYYLOGMGSA-N
SMILES:C(CC(=O)C1=CC=C(F)C=C1)[C@@H]2[C@H](N(C2=O)C3=CC=C(F)C=C3)C4=CC=C(O)C=C4
Synonyms:- (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone
- (3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one
- 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-
- 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R-trans)-
- Ezetimibe Ketone
Sort by
Found 10 products.
(3R,4S)-1-(4-FLUOROPHENYL)-3-(3-(4-FLUOROPHENYL)-3-OXOPROPYL)-4-(4-HYDROXYPHENYL)AZETIDIN-2-ONE
CAS:Purity:95%Molecular weight:407.4169921875Ezetimibe ketone
CAS:Ezetimibe ketone (EZM-K) exhibits antioxidant activity and alleviates H2O2-induced NRK-52E cell apoptosis by upregulating Nrf2 and HO-1 levels.Formula:C24H19F2NO3Purity:99.32%Color and Shape:White Crystalline SolidMolecular weight:407.41Ezetimibe Ketone ((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFormula:C24H19F2NO3Color and Shape:White SolidMolecular weight:407.1333(3R,4S)-1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-4-(4-hydroxyphenyl)azetidin-2-one
CAS:Formula:C24H19F2NO3Purity:98%Color and Shape:SolidMolecular weight:407.4094Ezetimibe Ketone
CAS:Controlled ProductImpurity Ezetimibe Ketone (USP) Applications Phase-I metabolite of Ezetimibe (E975000). References Shah, V., et al: J. Pharm. Sci., 17, 1551 (2000), Van Heek, M., et al.: Br. J. Pharmacol., 134, 409 (2001), Watts, G., et al.: Clin. Sci.,103, 595 (2002), Ghosal, A., et al.: Drug Metab. Dispos., 32, 314 (2004), Sistla, R., et al.: J. Pharm. Biomed. Anal., 39, 517 (2005),Formula:C24H19F2NO3Color and Shape:WhiteMolecular weight:407.41Ezetimibe ketone
CAS:Ezetimibe ketone is a lipid-lowering agent that inhibits cholesterol absorption through the inhibition of Niemann-Pick C1-like 1 (NPC1L1). Ezetimibe ketone is used to reduce the levels of low-density lipoprotein cholesterol (LDL-C) in patients with primary hypercholesterolemia, sitosterolemia, and familial combined hyperlipidemia. Ezetimibe ketone has been shown to be bioequivalent to ezetimibe, which is an oral drug that inhibits cholesterol absorption by blocking NPC1L1. The drug binds to the NPC1L1 receptor in the brush border membrane of enterocytes and prevents cholesterol uptake. Ezetimibe ketone has a high solubility in organic solvents such as dichloromethane or chloroform. It also has a high melting point, which makes it suitable for use on chromatographic columns.Formula:C24H19F2NO3Purity:Min. 95%Color and Shape:PowderMolecular weight:407.41 g/mol
