CAS 191547-12-3: (5alpha,7beta,9alpha,10beta)-7,9,10-tris(acetyloxy)-13-oxotaxa-4(20),11-dien-5-yl (2E)-3-phenylprop-2-enoate

2-Deacetoxytaxinine B is a diterpenoid compound, which is a naturally occurring taxane. It is sourced from the bark of yew trees, primarily Taxus species, where it exists as a secondary metabolite. The mode of action for 2-Deacetoxytaxinine B involves interference with microtubule dynamics, similar to other taxanes, which disrupts cell division and can potentially inhibit cancer cell proliferation. This compound carries significance in the realm of cancer research due to its structural similarity to other well-known taxanes like paclitaxel and docetaxel, which are clinically used as chemotherapeutic agents. Although not used directly in clinical settings, 2-Deacetoxytaxinine B serves as a precursor in synthetic routes for more potent derivatives. It is also valuable in biological and pharmacological studies to explore novel anti-cancer strategies and understand the complex biosynthesis of taxanes. Moreover, its role in developing semi-synthetic taxanes could contribute to more efficient production processes for drugs aimed at targeting a range of malignancies.