(1E)-N'-Hydroxy-2-phenylethanimidamide, with the CAS number 19227-11-3, is an organic compound characterized by its imidamide functional group and a hydroxyl group attached to the nitrogen atom. This compound typically exhibits properties associated with both amides and hydroxylamines, which may influence its reactivity and solubility. It is likely to be a solid at room temperature, with potential applications in medicinal chemistry due to its structural features that may interact with biological targets. The presence of the phenyl group suggests that it may exhibit aromatic characteristics, contributing to its stability and potential for π-π stacking interactions. Additionally, the hydroxyl group can participate in hydrogen bonding, which may enhance its solubility in polar solvents. Overall, (1E)-N'-hydroxy-2-phenylethanimidamide is of interest for its potential biological activity and as a building block in organic synthesis. Further studies would be necessary to fully elucidate its properties and applications in various chemical contexts.

(1E)-N'-HYDROXY-2-PHENYLETHANIMIDAMIDE

19227-11-3: N'-Hydroxy-2-phenylethaneimideamide, N'-hydroxy-2-phenylethanimidamide

N-Hydroxy-2-phenyl-acetamidine

Benzeneethanimidamide, N-hydroxy-

2-Phenylacetamidoxime

N'-Hydroxy-2-phenylethanimidamide (NHPEEA) is a drug that inhibits the transcription factor HIF-1α, which regulates the expression of genes involved in cellular response to hypoxia. NHPEEA has been shown to inhibit tumor growth and metastasis in cellular and xenograft models. It was also shown to inhibit the proliferation of Skov3 cells under hypoxic conditions.

CAS 19227-11-3: (1E)-N'-HYDROXY-2-PHENYLETHANIMIDAMIDE

N-Hydroxy-2-phenyl-acetamidine

Ref: 10-F033305

Benzeneethanimidamide, N-hydroxy-

Ref: IN-DA002FSK

2-Phenylacetamidoxime

Ref: 54-OR346070

N'-Hydroxy-2-phenylethanimidamide

Ref: 3D-FH165475