Pyridoxal-phosphate-6-azophenyl-2',4'-disulfoni, identified by its CAS number 192575-19-2, is a chemical compound that serves as a derivative of pyridoxal phosphate, which is the active form of vitamin B6. This compound features a pyridoxal moiety linked to an azophenyl group and contains disulfide functionalities, contributing to its unique chemical properties. It is characterized by its potential role in biochemical applications, particularly in enzyme catalysis and as a cofactor in various metabolic processes. The presence of the azophenyl group may impart specific optical properties, making it useful in spectroscopic studies. Additionally, the disulfide bond can participate in redox reactions, influencing the compound's reactivity and stability. Overall, pyridoxal-phosphate-6-azophenyl-2',4'-disulfoni is of interest in both biochemical research and potential therapeutic applications, although detailed studies on its specific biological activities and interactions are necessary for a comprehensive understanding of its utility.

pyridoxal-phosphate-6-azophenyl-2',4'-  disulfoni

PPADS is a pyridoxal phosphate-dependent adenosine diphosphate (ADP) ribose hydrolase inhibitor that blocks the formation of the second messenger, cyclic ADP-ribose. It has been shown to inhibit neuronal death in vitro and in vivo models, as well as reducing chronic cough. The synergistic effect of PPADS with other pharmacological agents has also been studied. PPADS inhibits cyclase activity by blocking the binding site on the enzyme for ATP, thereby preventing cAMP production. In addition, PPADS prevents intracellular calcium increase by antagonizing purinergic P2Y receptors.

PPADS tetrasodium

PPADS Tetrasodium

PPADS tetrasodiuma is a P2X receptor antagonist and an inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle.

CAS 192575-19-2: pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni

PPADS tetrasodium

Ref: 3D-SHA57519

PPADS Tetrasodium

Ref: IN-DA01CC9J

PPADS tetrasodium

Ref: TM-T16564