CAS: 1957235-66-3

4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione is a potent inhibitor of voltage-gated potassium channels. It blocks the delayed rectifier K+ current with an IC50 of 2 nM. 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione has been shown to be a ligand for the NMDA receptor and the glycine receptor. The IC50 for binding to these receptors is in the range of 1 nM. 4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3piperidinyl)-1H isoindole 1, 3 ( 2 H ) -

Pomalidomide-C2-NH2 is a synthetic E3 ligase ligand-linker with a cereblon ligand.

Pomalidomide-C2-NH2