CAS 199327-61-2: 7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one
Formula:C16H21N3O4
InChI:InChI=1S/C16H21N3O4/c1-21-14-10-13-12(16(20)18-11-17-13)9-15(14)23-6-2-3-19-4-7-22-8-5-19/h9-11H,2-8H2,1H3,(H,17,18,20)
InChI key:InChIKey=WFUBWLXSYCFZEH-UHFFFAOYSA-N
SMILES:O=C1C=2C(=CC(OC)=C(OCCCN3CCOCC3)C2)NC=N1
Synonyms:- 4(1H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]-
- 4(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]-
- 7-Methoxy-6-(3-Morpholinopropoxy)Quinazolin-4(3H)-One
- 7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one
- 7-Methoxy-6-(3-morpholinopropoxy)quinazolin-4-one
- 7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(3H)-quinazolinone
- 7-Methoxy-6-[3-(4-morpholinyl)propoxy]quinazolin-4(3H)-one
- 7-methoxy-6-(3-morpholin-4-yl-propoxy)-3H-quinazolin-4-one
- 7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(1H)-one
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Found 10 products.
Gefitinib EP Impurity A (Gefitinib USP Related Compound A)
CAS:Formula:C16H21N3O4Color and Shape:White To Off-White SolidMolecular weight:319.367-methoxy-6-[3-(morpholin-4-yl)propoxy]-1,4-dihydroquinazolin-4-one
CAS:Purity:98%Molecular weight:319.3609924316414(3H)-Quinazolinone, 7-methoxy-6-[3-(4-morpholinyl)propoxy]-
CAS:Formula:C16H21N3O4Purity:97%Color and Shape:SolidMolecular weight:319.3556Gefitinib Related Compound A (7-Methoxy-6-(3-morpholinopropoxy)quinazolin-4(3H)-one)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C16H21N3O4Color and Shape:White Yellow PowderMolecular weight:319.153217-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(3H)-one
CAS:7-Methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4(3H)-oneColor and Shape:SolidMolecular weight:319.36g/mol7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
CAS:The anti-cancer drug 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a potent apoptosis inducing agent that can induce cancer cell death. It was synthesized and characterized by x-ray crystallography, which showed that the molecule adopts a highly flexible conformation in solution. This amide binds to the membrane of cells, causing the release of annexin from the membrane and the subsequent activation of caspases, which causes cell apoptosis. 7MMQOQ has been shown to be effective against bone cancer and other types of cancer cells in vitro. 7MMQOQ also induces genes expression and death in cells, making it a potential candidate for cancer treatment.Formula:C16H21N3O4Purity:Min. 95%Molecular weight:319.36 g/molRef: 3D-FM42858
Discontinued product7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
CAS:Controlled ProductApplications Gefitinib intermediate. References Kelly, L., et al.: Cancer Cell., 1, 421 (2002), Pandey, A., et al.: J. Med. Chem., 45, 3772 (2002), Ciardiello, F., et al.: Exp. Opin Emerg. Drugs, 8, 501 (2003), Caponigro, F., et al.: Curr. Opin Oncol., 16, 225 (2004),Formula:C16H21N3O4Color and Shape:NeatMolecular weight:319.36
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