CAS 199864-86-3: RS-127445 Hydrochloride
Synonyms:- 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine hydrochloride
- 4-(4-Fluoro-1-naphthyl)-6-isopropylpyriMidin-2-aMine
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Found 6 products.
RS-127445 Hydrochloride
CAS:Formula:C17H16FN3·HClPurity:>98.0%(HPLC)Color and Shape:White to Orange to Green powder to crystalMolecular weight:317.79RS-127445 hydrochloride
CAS:RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).Formula:C17H17ClFN3Purity:99.48%Color and Shape:SolidMolecular weight:317.792-Pyrimidinamine, 4-(4-fluoro-1-naphthalenyl)-6-(1-methylethyl)-, hydrochloride (1:1)
CAS:Formula:C17H17ClFN3Purity:98%Color and Shape:SolidMolecular weight:317.7884RS 127445 hydrochloride
CAS:A selective antagonist of serotonin 5-HT2B receptors, inhibiting inositol phosphate formation and calcium release. Blocks 5-HT-induced contraction in rat stomach fundus. Reduces fecal output in vivo, upon inhibition of 5-HT2B by RS 127445, demonstrating a potential role for this receptor in colonic motility. Inhibits visceral hypersensitivity induced by restraint stress or colonic inflammation.Formula:C17H16FN3·HClPurity:Min. 95%Color and Shape:White To Yellow SolidMolecular weight:317.79 g/mol
