CAS 2005-43-8: 2-Bromoquinoline

2-Bromoquinoline

2-Bromoquinoline is an antimicrobial agent that binds to bacterial receptors. It is a bifunctional molecule with two reactive groups: a hydroxyl group and a nitrogen atom. 2-Bromoquinoline has been shown to inhibit the growth of various bacteria, including Mycobacterium tuberculosis, Staphylococcus epidermidis and Streptococcus pyogenes, by preventing the formation of a proton gradient across the bacterial membrane. 2-Bromoquinoline also inhibits hyperproliferative diseases such as amyloidosis in mice by binding to amyloid fibrils. This drug has been shown to cause DNA damage in mammalian cells, which may be due to its ability to form hydrogen bonds with methyl ethyl groups on DNA bases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.