CAS 20082-71-7: Chlorodimethyl(pentafluorophenyl)silane

(Chloro)(perfluorophenyl)dimethylsilane

Pentafluorophenyldimethylchlorosilane is a chemical compound that has been shown to have ovarian activity in mice. This compound was tested in a two-way crossover study with diode laser ablation and chromatographic sample preparation. The intraperitoneal administration of pentafluorophenyldimethylchlorosilane to mice resulted in an increase of the 2,4-dichlorobenzoic acid concentration in urine samples. Pentafluorophenyldimethylchlorosilane is chemically stable and does not react with amines or hydrochloric acid. It also has a high chemical ionization yield, making it useful for the analysis of trace metal ions such as mercury and lead.

It is used as a GC reagent for detection of sterols at low concentration as flophemesyl derivatives, readily detected by electron capture. Chlorodimethyl(pentafluorophenyl)silane is an extremely sensitive derivatizing agent for the analysis of sterols and lower aliphatic alcohols by electron capture gas chromatography. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.