CAS: 2010159-47-2
Formula:C55H66ClN7O9S
InChI:InChI=1S/C55H66ClN7O9S/c1-34-27-46(60-43-18-16-42(56)17-19-43)45-28-41(15-20-47(45)63(34)36(3)64)38-11-13-40(14-12-38)52(67)57-21-22-70-23-24-71-25-26-72-32-49(66)61-51(55(4,5)6)54(69)62-31-44(65)29-48(62)53(68)58-30-37-7-9-39(10-8-37)50-35(2)59-33-73-50/h7-20,28,33-34,44,46,48,51,60,65H,21-27,29-32H2,1-6H3,(H,57,67)(H,58,68)(H,61,66)/t34-,44+,46+,48-,51+/m0/s1
InChI key:InChIKey=FYSWLIFIYIVHPI-DDWISSAJSA-N
SMILES:N([C@H]1C=2C(N(C(C)=O)[C@@H](C)C1)=CC=C(C2)C3=CC=C(C(NCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4)[C@@](C)(C)C)=O)=O)C=C3)C7=CC=C(Cl)C=C7
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Found 3 products.
MZP-54
CAS:MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)Formula:C55H66ClN7O9SPurity:98%Color and Shape:SolidMolecular weight:1036.67MZP-54
CAS:MZP-54 is a natural product that inhibits the HIV virus. It binds to HIV-1 integrase and blocks the integration of viral DNA into the host cell genome. MZP-54 has been shown to inhibit tumor growth in vitro and in vivo, as well as to reduce the number of cancer cells in culture. It also inhibits angiogenesis and has shown activity against a variety of human cancers, including prostate, breast, colon, lung, leukemia, and lymphoma. MZP-54 also inhibits expression of genes regulated by bromodomain proteins. Bromodomain proteins are involved in regulating gene expression by binding to acetylated lysine residues on histones H3 and H4. This protein is expressed at high levels in heart tissue and is associated with cardiotoxicity caused by coronary heart disease or heart failure. In addition, MZP-54 has been found to inhibit renal fibrosis and regulate erythropoietin production.Formula:C55H66ClN7O9SPurity:Min. 95%Molecular weight:1,036.67 g/mol
