
CAS 20125-39-7: N6-(2-phenylethyl)adenosine
Formula:C18H21N5O4
InChI:InChI=1/C18H21N5O4/c24-8-12-14(25)15(26)18(27-12)23-10-22-13-16(20-9-21-17(13)23)19-7-6-11-4-2-1-3-5-11/h1-5,9-10,12,14-15,18,24-26H,6-8H2,(H,19,20,21)
SMILES:c1ccc(cc1)CCNc1c2c(ncn1)n(cn2)C1C(C(C(CO)O1)O)O
Synonyms:- 9-pentofuranosyl-N-(2-phenylethyl)-9H-purin-6-amine
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N6-(2-Phenylethyl)adenosine
CAS:N6-(2-Phenylethyl)adenosine (N6-PEA) is an adenosine analogue that is a chemosensitive agent. It has been shown to inhibit cancer cell growth and to induce apoptosis in vitro. N6-PEA binds to the adenosine receptor and blocks viral replication, including human pathogens such as herpes simplex virus type 1 and 2, cytomegalovirus, and varicella zoster virus. N6-PEA also has antiviral effects against HIV type 1 in cell-based assays. It is hydrophobic and binds to the adenosine receptor with high affinity. N6-PEA was modeled using molecular dynamics simulations with a combination of computational chemistry techniques, which revealed its binding mode at the adenosine receptor site.Formula:C18H21N5O4Purity:Min. 95%Molecular weight:371.39 g/molN6-(2-Phenylethyl)adenosine
CAS:N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM forFormula:C18H21N5O4Purity:99.94%Color and Shape:SolidMolecular weight:371.39N6-(2-Phenylethyl)adenosine
CAS:Formula:C18H21N5O4Purity:≥ 95.0%Color and Shape:White to off-white powderMolecular weight:371.39