CAS 2021-28-5: Ethyl 3-phenylpropanoate

Ethyl 3-phenylpropionate is a clear, colorless liquid with a fruity odor. It has been used in the production of perfumes and as a solvent. The compound is also known to be used in the synthesis of other organic compounds and can be found in dry weight. Palladium complexes are formed when ethyl 3-phenylpropionate is mixed with palladium chloride or palladium acetate. Ethyl 3-phenylpropionate is an intermediate in the conversion of ethyl decanoate to methyl anthranilate by diethyl succinate and p. pastoris. This conversion takes place at room temperature and below the phase transition temperature (T). The compound has been shown to have low lp-pla2 activity, which may be due to its lack of hydroxyl group.

Applications Ethyl 3-Phenylpropionate is also used in the synthesis pyrimidine based inhibitors of cyclin-dependant kinases. It is also used to preparation of inhibitor BB-3497. References Markwalder, J. et al.: J. Med. Chem., 47, 5894 (2004); Davies, S. et al.: Bioorg. Med. Chem. Lett., 13, 2709 (2003);

Ethyl 3-phenylpropanoate

Ethyl 3-phenylpropionate is used as an active pharmaceutical ingredient intermediate. It is also used in the synthesis of pyrimidine based inhibitors of cyclin-dependant kinases. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.