7-Nitrobenz[a]anthracene is a polycyclic aromatic hydrocarbon (PAH) characterized by its complex structure, which includes a nitro group attached to a benz[a]anthracene framework. This compound is known for its mutagenic and carcinogenic properties, making it a subject of study in environmental and health-related research. It typically appears as a yellow to orange solid and is sparingly soluble in water but soluble in organic solvents. The presence of the nitro group significantly influences its reactivity and biological activity, contributing to its potential as a DNA intercalator. 7-Nitrobenz[a]anthracene is often used in laboratory settings to investigate mechanisms of mutagenesis and the effects of PAHs on living organisms. Due to its hazardous nature, proper safety precautions are essential when handling this compound, including the use of personal protective equipment and adherence to regulatory guidelines for disposal and exposure.

7-Nitrobenz[a]anthracene

20268-51-3: 7-Nitrobenz[a]anthracene, 7-Nitrobenzo[a]anthracene, Benz[A]Anthracene, 7-Nitro-, 7-Nitrotetraphene

Benz[a]anthracene, 7-nitro-

7-Nitrobenz[A]anthracene is an aromatic hydrocarbon that is a potent carcinogen. It is used as a standard in chromatographic science to measure the rate of oxidation and to identify the oxidation products. 7-Nitrobenz[A]anthracene has been shown to induce tumors in rats, but not in mice. The mechanism of tumorigenicity may be due to its ability to bind covalently with DNA. 7-Nitrobenz[A]anthracene binds stereoselectively with nitro groups on proteins, which can lead to the formation of carcinogenic nitrosamines. It also adsorbs to silica gel and other polar surfaces, so it can be removed by adsorption chromatography or supercritical fluid extraction.

CAS 20268-51-3: 7-Nitrobenz[a]anthracene

Benz[a]anthracene, 7-nitro-

Ref: IN-DA0028CY

7-Nitrobenz[A]anthracene standard

Ref: 3D-VAA26851

7-Nitrobenz[a]anthracene

Ref: TR-DRE-C20962600

7-Nitrobenz[a]anthracene

Ref: 04-C20962600