CAS 2040-26-8: 1-(4-methoxyphenyl)-2,2-dimethylpropan-1-one

1-(4-Methoxyphenyl)-2,2-dimethylpropan-1-one is a bioorganic compound with the formula CHClO. It is an aromatic ketone that is used in organic synthesis. The compound is prepared by acylation of 4-methoxybenzaldehyde with chloroacetyl chloride in the presence of aluminum chloride as a catalyst. The reaction is catalyzed by light and proceeds quantitatively at room temperature, affording 1-(4-methoxyphenyl)-2,2-dimethylpropan-1-one in nearly quantitative yield. Friedel-Crafts acylation can be used to synthesize derivatives of this compound, such as benzoyl derivatives. The reaction takes place at room temperature under mild conditions and typically gives products in high yields. The reaction time for Friedel-Crafts acylation depends on the reactivity of the substrate but typically ranges from one to several hours,