CAS 2052-01-9: Bromoisobutyric acid

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2-Bromoisobutyric acid is used in the synthesis of dextran macroinitiator for atom transfer radical polymerization (ATRP) by partial esterification of hydroxyl group of the polysaccharide. The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Bromo-2-methylpropionic acid

Applications 2-Bromoisobutyric Acid is used in the Herceptin functionalization of polyhedral oligomeric silsesquioxane-conjugated oligomers-silica /iron oxide nanoparticles for tumor cell sorting. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Mi, Y. et al.: Biomat. 32, 8226 (2011);

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

2-Bromo-2-methylpropionic acid is a chemical compound that is used to stabilize nanoparticles. It also has covalent interactions with the surface of the nanoparticles, which helps to stabilize them and prevent aggregation. 2-Bromo-2-methylpropionic acid can be modified with polymers or other molecules that can help to stabilize the particles. This stabilizer is also able to create magnetic nanoparticles by using a strategy called "magnetic stabilization". In this method, the stabilizer can react with the metal ions in solution and form a stable complex, which will then coat the particles of interest. The stabilizer can also be used to circumvent mesoporous materials, such as silica gel, by coating them with a polymer layer.