CAS 205687-01-0: Capsiate

Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant,

Capsiate is a bioactive compound derived from a specific variety of sweet peppers known for its non-pungency. It acts by enhancing thermogenesis and lipid metabolism, primarily due to its ability to activate the TRPV1 receptor without causing the typical burning sensation associated with capsaicin. Capsiate facilitates the upregulation of energy expenditure by increasing the body’s metabolic rate, which subsequently encourages the oxidation of fats. This thermogenic effect does not stimulate the sympathetic nervous system to the degree that traditional capsaicinoids do, offering a more tolerable alternative for research and potential therapeutic applications. Capsiate's utility is explored in various scientific studies aimed at investigating its role in weight management, obesity research, and metabolic health. Researchers have found interest in its application for probing metabolic pathways, its influence on energy balance, and potential therapeutic roles in metabolic disorders. By avoiding the pungency of other capsaicin-related compounds, capsiate provides a unique opportunity to study the mechanisms of fat metabolism without the adverse effects commonly associated with capsaicin consumption.