CAS: 2060610-53-7

(2R)-2-(5-Fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide is a peptide that belongs to the class of inhibitors. It has been shown to inhibit ion channels in cells. The compound has an IC50 of about 0.25 μM for the hERG channel and shows no activity against other ion channels tested such as NMDA, GABA A , and Na V 1.8. (2R)-2-(5 -fluoro-- 2 -hydroxyphenyl)-2-[1 -oxo-- 6 - (4-- piperazin-- 1-- ylphenyl)-- 1,3 -dihydro-- 2H

JBJ-04-125-02: Oral EGFR inhibitor, targets EGFRL858R/T790M with 0.26 nM IC50, halts cancer growth, anti-tumor.