CAS 20633-67-4: calycosin-7-o-beta-d-glucoside
Formula:C22H22O10
InChI:InChI=1/C22H22O10/c1-29-15-5-2-10(6-14(15)24)13-9-30-16-7-11(3-4-12(16)18(13)25)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1
Synonyms:- 3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside
- 4H-1-benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-
- Calycosin-O-Glucopyranoside
- Calycosin 7-O-Glucoside
- Calycosin 7-O-β-D-glucopyranoside
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Found 9 products.
calycosin-7-O-β-D-glucoside
CAS:Calycosin-7-O-β-d-glucoside(CG) treatment can significantly reduce infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia-reperfusion rat model; inhibit the expression and activities of MMPs, and secure the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex; scavenge NO, inhibit the activities of MMP-2 and MMP-9, and attenuate cell death in the in vitro cultured brain microvascular endothelial cells under OGD condition; thus CG could protect BBB integrity in experimental cerebral ischemia-reperfusion injury via regulating NO/cav-1/MMPs pathway.Formula:C22H22O10Purity:95%~99%Color and Shape:PowderMolecular weight:446.408Calycosin 7-O-β-D-Glucopyranoside (3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen7-yl β-D-glucopyranoside)
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFormula:C22H22O10Color and Shape:PowderMolecular weight:446.1213Calycosin-7-O-β-D-glucoside
CAS:Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity.Formula:C22H22O10Purity:98% - 99.69%Color and Shape:SolidMolecular weight:446.4Ref: TM-T3388
1mg47.00€5mg92.00€10mg144.00€25mg254.00€50mg424.00€100mg613.00€500mg1,264.00€1mL*10mM (DMSO)97.00€Calycosin 7-O-Beta-D-glucoside
CAS:Controlled ProductApplications Calycosin 7-O-β-D-glucoside is one of seven constituent in Guanjiekang (GJK) that is formed by five medicinal herbs that is used for the rheumatoid arthritis (RA). References Wu, J., et al.: Mol., 21, 1732/1-1732/12 (2016)Formula:C22H22O10Color and Shape:NeatMolecular weight:446.40Calycosin 7-glucoside
CAS:Natural glycosideFormula:C22H22O10Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:446.414H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)-
CAS:Formula:C22H22O10Purity:98%Color and Shape:SolidMolecular weight:446.4041Calycosin-7-O-β-D-glucoside
CAS:Calycosin-7-O-β-D-glucoside is a flavonoid glycoside, which is primarily derived from the root of Astragalus membranaceus, a plant widely used in traditional Chinese medicine. This compound is characterized by its antioxidative and anti-inflammatory activities, mediated through modulation of various signaling pathways in the body, such as the MAPK and NF-κB pathways. It plays a significant role in scavenging free radicals and inhibiting inflammatory mediators, thus contributing to cellular protection and reducing oxidative stress. Research indicates that Calycosin-7-O-β-D-glucoside may be leveraged in pharmacological contexts for its potential to enhance immune responses, protect against cardiovascular diseases, and offer neuroprotective effects. Its ability to modulate enzyme activities and gene expression underscores its extensive applicability in therapeutic interventions. Investigations continue into its efficacy and mechanism of action, with an emphasis on developing novel treatments for chronic inflammatory conditions and degenerative diseases.Formula:C22H22O10Purity:Min. 95%Color and Shape:White PowderMolecular weight:446.4 g/mol
