CAS 2065-66-9: Phosphonium, methyltriphenyl-, iodide (1:1)

Methyl(trisphenyl)phosphonium iodide

Methyltriphenylphosphonium Iodide is a fluorescent compound used in electrochemical impedance spectroscopy to monitor the transport of glucose across the mitochondrial membrane. It is also used as an inhibitor for quinoline derivatives, which are often used as anticancer agents. Methyltriphenylphosphonium Iodide has been shown to inhibit glucose transport by inhibiting the enzyme hexokinase, which catalyzes the conversion of glucose to glucose-6-phosphate. In addition, this molecule binds to the amide region of its receptor and blocks the binding site for ATP, preventing phosphorylation reactions that regulate ion channels and neurotransmitter release.

Applications (Methyl)triphenylphosphonium Iodide is the precursor to a wittig reagent.

Methyltriphenylphosphonium iodide is as a reactant for synthesis of triphenylamine-based dyes and polyolefinic aromatic molecules with pyrene for use in dye-sensitized solar cells. Used as ligand in coupling reaction. It is also used as a precursor to a Wittig reagent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.