Sodium 2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonate hydrate, identified by its CAS number 207399-16-4, is a chemical compound that features a sulfonate group attached to an indole structure, which is known for its diverse biological activities. This compound typically appears as a crystalline solid and is soluble in water, making it useful in various applications, including biochemical research and pharmaceutical formulations. The presence of the dioxo and sulfonate functional groups contributes to its reactivity and potential interactions with biological molecules. As a hydrate, it contains water molecules in its crystalline structure, which can influence its stability and solubility. The compound may be utilized in studies related to enzyme inhibition, drug development, or as a reagent in organic synthesis. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper laboratory practices are followed.

sodium 2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonate hydrate

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Isatin-5-sulfonic acid sodium salt dihydrate is a potent inhibitor of caspases. It has been shown to inhibit the activity of caspase-3 in vitro, thereby inhibiting apoptosis. Isatin-5-sulfonic acid sodium salt dihydrate has also been shown to increase survival rates in animal models of neurodegenerative diseases such as Parkinson's disease and Huntington's disease. Isatin-5-sulfonic acid sodium salt dihydrate may have neuroprotective effects by inhibiting the release of proinflammatory cytokines and nitric oxide, which are associated with neuronal death. This drug also inhibits monoamine oxidase A (MAO-A) and zymosterone B (ZVAD).

CAS 207399-16-4: sodium 2,3-dioxo-2,3-dihydro-1H-indole-5-sulfonate hydrate

Isatin-5-sulfonic acid sodium salt dihydrate

Ref: 3D-FI31420

Isatin-5-Sulfonic Acid Sodium Salt Dihydrate

Ref: ST-EA-CP-I43007

1H-Indole-5-sulfonic acid, 2,3-dihydro-2,3-dioxo-, sodium salt, hydrate (1:1:2)

Ref: IN-DA002J10