CAS: 2079892-79-6

N-[8-[[(3S)-4-(Cyclopentylcarbonyl)-3-methyl-1-piperazinyl]methyl]-7-methylimidazo[1,2-a]pyridin-6-yl]-2-methyl-5-pyrimidinecarboxam ide is a peptide that activates ion channels and inhibits protein interactions. It is used as a research tool in the fields of cell biology, pharmacology, and immunology. This peptide is an inhibitor for the receptor for the neurotransmitter acetylcholine. It has been shown to be a ligand for the nicotinic acetylcholine receptor alpha subunit and can also inhibit protein interactions with other proteins.

RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist(human RORγt-LBD with an IC50 of 19 nM).