CAS: 2095433-94-4

N-(3-((5-Chloro-4-(1H-Indol-3-Yl)Pyrimidin-2-Yl)Amino)Phenyl)-4-(4-(Dimethylamino)But-2-Enamido)Benzamide Dihydrochloride

(E/Z)-THZ1 2HCl

THZ1 dihydrochloride is a drug that has been shown to be effective in the treatment of kidney disease. It is an analog of the natural amino acid L-arginine and can be used to treat diseases where there is a significantly reduced amount of nitric oxide, such as polycystic kidney disease. This drug stabilizes the blood vessels and capillaries by increasing their production of nitric oxide, which leads to increased blood flow. THZ1 dihydrochloride also prevents atherosclerosis by inhibiting lipid accumulation in the cells.

THZ1 2HCl: selective CDK7 allosteric inhibitor, IC50 3.2 nM, hinders cancer cell growth.