CAS: 210302-17-3

BAM15 is a pharmacological agent that acts on mitochondrial membrane potential. It binds to the mitochondrial membrane and blocks proton flow, leading to the inhibition of cellular respiration. This leads to an increase in reactive oxygen species (ROS) production and mitochondrial membrane depolarization. BAM15 has been shown to have beneficial effects on hepatic steatosis and physiological changes in rats. It has also been shown to be effective against bowel diseases like colitis and necrotizing enterocolitis in vivo models. BAM15 is a promising drug for the treatment of congestive heart failure due to its ability to inhibit ATP synthesis in cardiac myocytes.

BAM 15

BAM 15 is an uncoupler of mitochondrial protonophore.