CAS 212631-67-9: PD184161
Formula:C17H13BrClF2IN2O2
InChI:InChI=1S/C17H13BrClF2IN2O2/c18-11-6-10(17(25)24-26-7-8-1-2-8)16(15(21)14(11)20)23-13-4-3-9(22)5-12(13)19/h3-6,8,23H,1-2,7H2,(H,24,25)
InChI key:InChIKey=VJNZMSLGVUSPCF-UHFFFAOYSA-N
SMILES:N(C1=C(C(NOCC2CC2)=O)C=C(Br)C(F)=C1F)C3=C(Cl)C=C(I)C=C3
Synonyms:- 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
- PD 184161
- Benzamide, 5-bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-
- 5-Bromo-2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide
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Found 7 products.
5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-Difluorobenzamide
CAS:5-Bromo-2-((2-Chloro-4-Iodophenyl)Amino)-N-(Cyclopropylmethoxy)-3,4-DifluorobenzamidePurity:99%Molecular weight:557.56g/molPD-184161
CAS:Controlled ProductApplications PD-184161 is a novel mitogen-activated protein kinase kinase (MEK) inhibitor shown to exhibit antitumor effects and suppress MEK-extracellular signal-related kinase signaling activity and cell proliferation in human hepatocellular carcinoma cells and in human hepatocellular carcinoma xenografts. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Yip-Schneider, M.T. et al.: J. Pharmacol. Exp. Therap., 329, 1063 (2009); Klein, P.J. et al.: Neoplasia, 8, 1 (2006); Yung, H.W. et al.: Biochem. Pharmacol., 68, 351 (2004);Formula:C17H13BrClF2IN2O2Color and Shape:NeatMolecular weight:557.5556PD184161
CAS:PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].Formula:C17H13BrClF2IN2O2Purity:99.40%Color and Shape:SolidMolecular weight:557.56Ref: TM-T21635
1mg38.00€2mg52.00€5mg79.00€10mg126.00€25mg273.00€50mg454.00€100mg653.00€200mg938.00€500mg1,406.00€PD 184161
CAS:Inhibitor of MEK kinasesFormula:C17H13BrClF2IN2O2Purity:Min. 95%Molecular weight:557.56 g/mol
