2-Naphthylmagnesium bromide is an organomagnesium compound, specifically a Grignard reagent, characterized by its naphthyl group bonded to a magnesium atom, which is also associated with a bromide ion. This compound typically appears as a colorless to light yellow solution when dissolved in an appropriate solvent, such as diethyl ether or tetrahydrofuran. It is highly reactive, particularly with water and moisture, leading to the formation of naphthalene and magnesium hydroxide, which makes it essential to handle under an inert atmosphere. 2-Naphthylmagnesium bromide is utilized in organic synthesis for the formation of carbon-carbon bonds, allowing for the introduction of the naphthyl group into various organic molecules. Its reactivity can be attributed to the nucleophilic nature of the naphthyl anion, which can attack electrophiles, facilitating a range of synthetic transformations. Due to its reactivity, it is crucial to store this compound in a dry, airtight container to prevent degradation and ensure safety during handling.

2-Naphthylmagnesium bromide

21473-01-8: Magnesium Bromide Naphthalen-2-Ide (1:1:1)

2-Naphthylmagnesium bromide is a chloroformate that is used in the synthesis of polyenes, which are substances with antibacterial activity. 2-Naphthylmagnesium bromide reacts with phosphite to form a diketone and then undergoes cross-coupling with an aromatic compound, such as naphthalene. The reaction products are chloride and an isomeric binaphthyl. This process can be reversed by reacting the product with sodium carbonate to form a ring-opening reaction. 2-Naphthylmagnesium bromide is also used as an imaging technique for brain imaging.

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CAS 21473-01-8: 2-Naphthylmagnesium bromide

2-Naphthylmagnesium bromide

Ref: 3D-WAA47301

2-Naphthylmagnesium bromide, 0.5M solution in THF, AcroSeal™

Ref: AC-43174