CAS 21499-66-1: (1beta,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione
Formula:C20H26O9
InChI:InChI=1S/C20H26O9/c1-7-4-9(21)13(23)17(2)8(7)5-10-19-6-28-18(3,14(24)11(22)12(17)19)20(19,27)15(25)16(26)29-10/h4,8,10-15,22-25,27H,5-6H2,1-3H3/t8-,10+,11+,12+,13+,14-,15-,17-,18+,19+,20+/m0/s1
InChI key:InChIKey=JBDMZGKDLMGOFR-KQSRGDCESA-N
SMILES:O[C@]12[C@@]34[C@@]([C@]5(C)[C@@](C[C@]3(OC(=O)[C@@H]1O)[H])(C(C)=CC(=O)[C@H]5O)[H])([C@@H](O)[C@H](O)[C@@]2(C)OC4)[H]
Synonyms:- (1β,11β,12α,15β)-13,20-Epoxy-1,11,12,14,15-pentahydroxypicras-3-ene-2,16-dione
- 5H-3,11cβ-(Epoxymethano)phenanthro[10,1-bc]pyran-5,10(6aβH)-dione, 1,2,3,3a,4,7,7aα,11,11a,11bα-decahydro-1β,2α,3aβ,4β,11β-pentahydroxy-3α,8,11aβ-trimethyl-, (-)-
- Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11β,12α,15β)-
- Bruceine D
- NSC 318801
- picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1beta,11beta,12alpha,15beta)-
- (1beta,11beta,12alpha,15beta)-1,11,12,14,15-Pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione
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Found 6 products.
Bruceine D
CAS:Bruceine D is a quassinoid compound, which is derived from the seeds of the Brucea javanica plant, known for its medicinal properties. It is predominantly sourced from traditional Chinese medicine where the plant is celebrated for its therapeutic benefits. The mode of action of Bruceine D involves the induction of apoptosis in cancer cells, through the disruption of mitochondrial function and the modulation of multiple cellular signaling pathways. Extensive research highlights its potential uses in the treatment of various cancers, primarily due to its ability to inhibit cell proliferation and induce cell death in malignant cells. Bruceine D is also studied for its anti-inflammatory and anti-malarial activities. Its role in these applications is critical as it provides a natural alternative for pharmacological interventions. The compound has sparked interest for targeted research into drug development, promising a novel approach in cancer therapy by leveraging its natural origin and distinctive mechanism of action.Formula:C20H26O9Purity:Min. 95%Molecular weight:410.42 g/molBruceine D
CAS:Bruceine D has anti-cancer activity, it inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.Bruceine D may have the potential to be used as a natural viricide, or a lead compound for new viricides.Formula:C20H26O9Purity:98%Molecular weight:410.419
