2-Chloro-N-(4-ethoxyphenyl)acetamide, with the CAS number 2153-08-4, is an organic compound characterized by its amide functional group and the presence of a chloro substituent. This compound features a chloro group attached to the second carbon of the acetamide structure, while the nitrogen atom is bonded to a 4-ethoxyphenyl group, which contributes to its overall hydrophobic character. The ethoxy group enhances the compound's solubility in organic solvents. Typically, compounds of this nature exhibit moderate to low toxicity and may possess biological activity, making them of interest in pharmaceutical research. The presence of the chloro substituent can influence the compound's reactivity and stability, potentially affecting its interactions in biological systems. Additionally, the molecular structure suggests that it may participate in hydrogen bonding due to the amide group, which can impact its physical properties such as melting point and boiling point. Overall, 2-chloro-N-(4-ethoxyphenyl)acetamide is a compound of interest in various chemical and biological applications.

2-chloro-N-(4-ethoxyphenyl)acetamide

2153-08-4: 2-Chloro-4′-ethoxyacetanilide, Acetamide, 2-chloro-N-(4-ethoxyphenyl)-, N-Chloroacetyl-4-ethoxyaniline, NSC 46900, p-Acetophenetidide, 2-chloro-, α-Chloro-p-ethoxyacetanilide

2-Chloro-N-(4-ethoxy-phenyl)-acetamide

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2-Chloro-N-(4-ethoxyphenyl)acetamide

2-Chloro-N-(4-ethoxyphenyl)acetamide (CETPA) is a synthetic compound that has been shown to have antimycobacterial activity. It binds to the active site of enzymes in the cell wall of Mycobacterium tuberculosis, inhibiting the synthesis of mycolic acids and thus leading to cell death. CETPA can also bind to the active sites of enzymes in the cell wall of Pseudomonas aeruginosa, resulting in inhibition of bacterial growth. 2-Chloro-N-(4-ethoxyphenyl)acetamide has analgesic properties and can be used as a topical agent for pain relief from minor aches and pains. It also has an antituberculosis effect, which may be due to its ability to inhibit DNA synthesis through hydrogen bonding with thymine residues. This drug is metabolized by dehydrating conjugation with chloride ions and elimination by renal excretion.

CAS 2153-08-4: 2-chloro-N-(4-ethoxyphenyl)acetamide

2-Chloro-N-(4-ethoxy-phenyl)-acetamide

Ref: 10-F026031

2-Chloro-N-(4-ethoxyphenyl)acetamide

Ref: 3D-CAA15308

2-chloro-n-(4-ethoxyphenyl)acetamide

Ref: 3D-FC59307