CAS 21598-06-1: 5-Hydroxyindole-2-carboxylic acid

5-Hydroxy-1H-indole-2-carboxylic acid

5-Hydroxyindole-2-carboxylic acid is a versatile building block that is used in the synthesis of complex compounds. It is also used as a reagent and speciality chemical. 5-Hydroxyindole-2-carboxylic acid can be used as an intermediate for the preparation of useful scaffolds, which are important for drug discovery and development. This compound has been shown to be useful in the synthesis of a variety of biologically active compounds, including high quality research chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

5-Hydroxyindole-2-carboxylic acid is a chemical species that belongs to the group of p-hydroxybenzoic acids. It is an intermediate in the synthesis of dopamine and melanin. 5-Hydroxyindole-2-carboxylic acid has been shown to inhibit the growth of cancer cells in vitro, which may be due to its ability to promote apoptosis. This compound also inhibits the production of eumelanin, which is responsible for black pigmentation in mammals. 5-Hydroxyindole-2-carboxylic acid has been shown to have anti-cholinergic properties and can be used for the treatment of chronic schizophrenia. 5HICA has also shown to have antioxidant properties due to its ability to reduce reactive oxygen species (ROS) and lipid peroxidation.