CAS: 2160546-07-4

IACS-13909

IACS-13909 (BBP-398), a specific and potent allosteric inhibitor of SHP2, that suppresses signaling through the MAPK pathway.

IACS-13909 is a drug that binds to EGFR and inhibits the kinase activity of EGFR. It is being developed as an anti-cancer drug for the treatment of cancer, with a particular focus on cancers that are resistant to ibrutinib. IACS-13909 has shown potent anticancer activity in preclinical studies, with no adverse effects on healthy cells. IACS-13909 has been used in clinical trials for the treatment of cancer, with promising results.