CAS: 2170606-74-1

DB2313 is a high-quality inhibitor of protein interactions that binds to the extracellular domain of the human receptor for advanced glycation endproducts (RAGE) with high affinity. DB2313 is an antibody-based peptide that can be used as a research tool or as a specific inhibitor of RAGE. It has been shown to inhibit the activation of RAGE in response to AGEs, which may be useful for the treatment of diabetes and other diseases.

DB2313

DB2313 is a potent PU.1 inhibitor (IC50=14 nM) that disrupts gene binding, induces AML cell apoptosis, and has anticancer properties.