CAS: 2172617-16-0

YKL-06-062

YKL-06-062 is a small molecule inhibitor, specifically targeting proteins involved in kinase signaling pathways. It is synthesized through chemical processes that ensure high specificity and efficacy. The mode of action involves the selective inhibition of kinases, thereby modulating phosphorylation states and influencing signal transduction within the cell. YKL-06-062 is predominantly used in research laboratories to dissect and understand cellular signaling pathways, particularly those related to cancer and other proliferative diseases. Its ability to interfere with kinase activity makes it a valuable tool in elucidating the mechanistic aspects of cell growth, differentiation, and apoptosis. Researchers utilize this compound to investigate the underlying molecular mechanisms and to potentially identify new therapeutic targets. The insights gained from studies using YKL-06-062 contribute to the broader understanding of cellular biology and disease pathology.

YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor that inhibits SIK1, SIK2 and SIK3 with IC50s of 2.12 nM, 1.40 nM and 2.86 nM.