CAS 21794-55-8: (+)-Daunomycinone
Formula:C21H18O8
InChI:InChI=1S/C21H18O8/c1-8(22)21(28)6-10-13(11(23)7-21)19(26)16-15(18(10)25)17(24)9-4-3-5-12(29-2)14(9)20(16)27/h3-5,11,23,25-26,28H,6-7H2,1-2H3/t11-,21-/m0/s1
InChI key:InChIKey=YOFDHOWPGULAQF-MQJDWESPSA-N
SMILES:O=C1C=2C(=C(O)C3=C(C2O)[C@@H](O)C[C@@](C(C)=O)(O)C3)C(=O)C=4C1=C(OC)C=CC4
Synonyms:- (+)-Daunomycinone
- (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione
- 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S-cis)-
- 5,12-naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-
- Daunomycin aglicone
- Daunomycinon
- Daunomycinone derivative
- Daunorubicin aglycone
- Daunorubicinone
- Leukaemomycinone C
- NSC 109351
- See more synonyms
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Found 9 products.
Daunorubicinone ((8S,10S)-8-Acetyl-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione)
CAS:Ketone-phenols and ketones with other oxygen functionFormula:C21H18O8Color and Shape:PowderMolecular weight:398.10017Daunomycinone
CAS:Daunomycinone (NSC-109351), a cancer-fighting antibiotic glycan, is derived from daunomycin and inhibits tumors.Formula:C21H18O8Purity:98.51%Color and Shape:SolidMolecular weight:398.36Epirubicin EP Impurity B (Daunorubicin EP Impurity A, Daunomycinone)
CAS:Formula:C21H18O8Molecular weight:398.37Daunomycinone
CAS:Applications Daunomycinone is the main metabolite of Daunorubicin (D194500). References Hjelle, J.T., et al.: J. Pharmacol. Exp. Therap., 229, 372 (1984); Prikrylova, V., et al.: J. Antibiotics, 38, 1714 (1985)Formula:C21H18O8Color and Shape:RedMolecular weight:398.36Daunomycinone
CAS:Daunomycinone is a chemical compound that belongs to the group of antitumor agents. It is used in cancer therapy and has been shown to inhibit protein synthesis, leading to cell death. Daunomycinone can be synthesized by reacting adriamycin with trifluoroacetic acid in the presence of an organic base. This reaction produces a daunomycinone molecule that has a hydroxyl group at one end and a carbonyl group at the other. The binding constants between daunomycinone and human serum proteins have been determined experimentally using molecular modeling techniques. Hydrogen bonding interactions are also present in this complex, which may account for its high affinity for proteins found in human serum.Formula:C21H18O8Purity:Min. 95%Color and Shape:Red PowderMolecular weight:398.36 g/mol
