DO3A, or 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid, is a polyaminocarboxylic acid that serves as a chelating agent, particularly for metal ions. It features a cyclic structure with four nitrogen atoms and three carboxylic acid groups, which allows it to effectively bind to various metal ions, making it useful in applications such as radiopharmaceuticals and metal ion separation. The compound is characterized by its high stability and selectivity for certain metal ions, including lanthanides and actinides, which is advantageous in nuclear medicine and imaging. DO3A is typically synthesized through multi-step organic reactions and is soluble in water, enhancing its utility in biological systems. Its ability to form stable complexes with metals is attributed to the chelation effect, which significantly reduces the toxicity of the metal ions while facilitating their transport in biological environments. Overall, DO3A is an important compound in both analytical chemistry and medical applications, particularly in the development of targeted therapies and diagnostic agents.

DO3A

217973-03-0: 1,4,7,10-Tetraazacyclododecaan-1,4,7-Triyltriazijnzuur

Applications DO3A is a macrocyclic chelating agent that can be used as a luminescent sensor to detect NAD(P)H based on Ln(III) ternary complexes.
References Smrcka, F., et.al., Molecules, 25, 4164, (2020); Zhou, X., et.al., Faming Zhuanli Shenqing, 14, (2020);


Please enquire for more information about Trisodium 2-[4,7-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trisodium 2-[4,7-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate

Sodium 2,2',2''-(1,4,7,10-Tetraazacyclododecane-1,4,7-Triyl)Triacetate

CAS 217973-03-0: DO3A

DO3A

Ref: TR-D494885

Trisodium 2-[4,7-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate

Ref: 3D-SIA97303

DO3A

Ref: IN-DA00BJQG

Sodium 2,2',2''-(1,4,7,10-Tetraazacyclododecane-1,4,7-Triyl)Triacetate

Ref: 54-OR1024699