5'-Guanylic acid, 8-bromo- is a modified nucleotide that plays a role in various biochemical processes, particularly in cellular signaling and as a building block for RNA synthesis. This compound is characterized by the presence of a guanine base, a ribose sugar, and a phosphate group, with the notable modification of a bromine atom at the 8-position of the guanine ring. The bromination can influence the compound's biological activity and stability, potentially affecting its interactions with enzymes and other biomolecules. It is soluble in water and exhibits properties typical of nucleotides, such as participating in hydrogen bonding and forming complexes with other nucleic acids. The CAS number 21870-09-7 uniquely identifies this substance in chemical databases, facilitating its study and application in research, particularly in the fields of molecular biology and pharmacology. Overall, 5'-Guanylic acid, 8-bromo- serves as an important tool in understanding nucleotide function and manipulation in various biological systems.

5'-Guanylic acid, 8-bromo-

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8-Bromoguanosine-5'-monophosphate (8BrGMP) is a nucleotide analog that modulates the expression of genes involved in circulatory and metabolic processes. 8BrGMP has been shown to be effective in clinical studies, including neonates with hypoxemia or low blood pressure. It also has a dose-dependent effect on the newborn's circulation and blood pressure, and can be used to treat neonatal transition. 8BrGMP is an advance in neonatal care due to its ability to improve oxygenation and promote better cardiovascular stability.

CAS 21870-09-7: 5'-Guanylic acid, 8-bromo-

8-Bromoguanosine-5'-monophosphate

Ref: 3D-NB71641