CAS: 218916-51-9

Euphorbia factor L2 is a sesquiterpene lactone that inhibits the growth of cancer cells by inducing autophagy, a process where cells degrade their own contents. This mechanism is activated through the induction of pro-apoptotic proteins and inhibition of anti-apoptotic proteins, leading to apoptosis. Euphorbia factor L2 also has pro-apoptotic effects on human leukemia cells and syncytial virus infection in mice. The drug is currently being investigated for its potential use in treating squamous cell carcinoma.

Euphorbia Factor L2

Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.