CAS: 2206736-04-9
Sort by
Found 4 products.
(2S)-1-(1-Oxo-2-propen-1-yl)-4-[5,6,7,8-tetrahydro-7-(8-methyl-1-naphthalenyl)-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-2-piperazineacetonitrile
CAS:Formula:C33H39N7O2Purity:98%Color and Shape:SolidMolecular weight:565.70846MRTX-1257
CAS:MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% target engagement.Formula:C33H39N7O2Purity:96.59% - 99.07%Color and Shape:SolidMolecular weight:565.71Ref: TM-T16143
1mg64.00€2mg89.00€5mg131.00€10mg220.00€25mg371.00€50mg557.00€100mg797.00€1mL*10mM (DMSO)170.00€MRTX-1257
CAS:MRTX-1257 is an inhibitor of protein tyrosine phosphatases, which are enzymes that dephosphorylate proteins on the surface of cells. MRTX-1257 is a covalent inhibitor that binds to the active site of these enzymes and prevents them from dephosphorylating specific proteins. This mechanism has been shown to have immunomodulatory effects in tumor tissue and to be effective against cancer. In addition, MRTX-1257 has been shown to inhibit pancreatic cancer growth in a mouse model. It also inhibits tumor cell proliferation by binding to cell receptors or altering their function.Formula:C33H39N7O2Purity:Min. 95%Molecular weight:565.71 g/mol
